Intact chitosan film was produced from Bradyporus sp. (Orthoptera, Insecta) and
characterized by Fourier Transform Infrared Spectroscopy (FTIR), Thermogravimetric
Analysis (TGA), X-ray diffractometer (XRD), Scanning Electron Microscopy (SEM) and
elemental analysis. MTT test was performed to determine the cytotoxic effects of chitosan.
Chitosan administered at optimal and overdose intervals was applied to HEK293 cells for 24,
48 and 72 hours. In the MTT cytotoxicity test, the IC 50 dose of chitosan was 1427 µM at 24
hours, 808.9 µM at 48 hours, and 611.6 µM at 72 hours. Considering all the conducted
analyses and cytotoxic experiments, the obtained intact novel chitosan film from the insects
could find applications for biotechnological applications.
Primary Language | English |
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Subjects | Biomaterial |
Journal Section | Research Article |
Authors | |
Publication Date | June 30, 2024 |
Submission Date | October 28, 2023 |
Acceptance Date | December 11, 2023 |
Published in Issue | Year 2024Volume: 8 Issue: 1 |
Aksaray J. Sci. Eng. | e-ISSN: 2587-1277 | Period: Biannually | Founded: 2017 | Publisher: Aksaray University | https://asujse.aksaray.edu.tr
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